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Literature summary for 2.7.7.B22 extracted from

  • Woodard, L.E.; Downes, L.M.; Lee, Y.C.; Kaja, A.; Terefe, E.S.; Wilson, M.H.
    Temporal self-regulation of transposition through host-independent transposase rodlet formation (2017), Nucleic Acids Res., 45, 353-366 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK-293 and HeLa cells and in mice Tribolium castaneum

Organism

Organism UniProt Comment Textmining
Tribolium castaneum
-
-
-

Synonyms

Synonyms Comment Organism
Buster
-
Tribolium castaneum
hAT transposase
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Tribolium castaneum

General Information

General Information Comment Organism
physiological function hAT transposase Buster forms filamentous structures, or rodlets, in human tissue culture cells, after gene transfer to adult mice, and ex vivo in cell-free conditions. GFP-laced rodlets in human cells form quickly in a dynamic process involving fusion and fission. Transposition declines after transposase concentrations become high enough for visible transposase rodlets to appear Tribolium castaneum